methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Base Information

Chemical Name:methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-
CAS No.:133635-06-0
Molecular Formula:C₂₈H₄₃Cl₆O₁₁PSi
Molecular Weight:827.42
Hs Code.:

methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-<bis(2,2,2-trichloroethyl)phosphate>

Synonyms:

Suppliers and Price of methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

There total 6 articles about methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17672-53-6
bis-(2,2,2-trichloroethyl)phosphorochloridate

: 133635-05-9
methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate

: 133635-06-0
methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Guidance literature:: With 1-methyl-1H-imidazole; In tetrahydrofuran; at 40 ℃; for 4h; Yield given;

Reference yield:

: 116464-73-4
methyl (methyl 5-O-benzyl-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid)onate

: 133635-06-0
methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Guidance literature:: Multi-step reaction with 6 steps

1: 61 percent / pyridine, DMAP / 15 h / 35 °C

2: 90 percent / aq. TFA, silica gel / CH₂Cl₂ / 5 h / Ambient temperature

3: 1) dibutyltin oxide, 2) tetrabutylammonium bromide / 1) benzene, reflux, 2 h, 2) benzene, 100 deg C, 16 h

4: 94 percent / N-methylimidazol / tetrahydrofuran / 24 h / 60 °C / the reaction was repeated

5: 90 percent / NaOCH₃ / methanol / 2 h / Ambient temperature

6: N-methylimidazole / tetrahydrofuran / 4 h / 40 °C

With pyridine; 1-methyl-1H-imidazole; dmap; tetrabutylammomium bromide; sodium methylate; silica gel; di(n-butyl)tin oxide; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 133635-02-6
methyl (methyl 4-O-benzoyl-5-O-benzyl-3-deoxy-α-D-manno-oct-2-ulopyranosid)onate

: 133635-06-0
methyl (methyl 5-O-benzyl-7-O-t-butyldimethylsilyl-3-deoxy-8-O-methyl-α-D-manno-oct-2-ulopyranosid)onate 4-

Guidance literature:: Multi-step reaction with 4 steps

1: 1) dibutyltin oxide, 2) tetrabutylammonium bromide / 1) benzene, reflux, 2 h, 2) benzene, 100 deg C, 16 h

2: 94 percent / N-methylimidazol / tetrahydrofuran / 24 h / 60 °C / the reaction was repeated

3: 90 percent / NaOCH₃ / methanol / 2 h / Ambient temperature

4: N-methylimidazole / tetrahydrofuran / 4 h / 40 °C

With 1-methyl-1H-imidazole; tetrabutylammomium bromide; sodium methylate; di(n-butyl)tin oxide; In tetrahydrofuran; methanol;