TC-E 5002

Base Information

Chemical Name:TC-E 5002
CAS No.:1453071-47-0
Molecular Formula:C₁₅H₂₇NO₄
Molecular Weight:285.384
Hs Code.:

Synonyms:

Suppliers and Price of TC-E 5002

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
TC-E 5002
10mg
$ 480.00

TRC
N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine
10mg
$ 185.00

Tocris
TC-E5002 ≥98%(HPLC)
50
$ 952.00

Tocris
TC-E5002 ≥98%(HPLC)
10
$ 227.00

TCI Chemical
N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine >80.0%(HPLC)
5mg
$ 210.00

Cayman Chemical
TC-E 5002 ≥98%
50mg
$ 786.00

Cayman Chemical
TC-E 5002 ≥98%
10mg
$ 185.00

Cayman Chemical
TC-E 5002 ≥98%
5mg
$ 110.00

Cayman Chemical
TC-E 5002 ≥98%
1mg
$ 26.00

ApexBio Technology
TC-E5002
10mg
$ 329.00

Total 8 raw suppliers

Chemical Property of TC-E 5002

Chemical Property:

Melting Point:87°C(lit.)
Boiling Point:457.3±47.0 °C(Predicted)
Density:1.130±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

TC-E 5002 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine is a selective histone demethylase KDM2/7 inhibitor used in tumor inhibition and suppression of cancer cell growth.

Technology Process of TC-E 5002

There total 5 articles about TC-E 5002 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 1454255-85-6
tert-butyl 3-(9-cyclopropyl-N-hydroxynonanamido)propanoate

: 1453071-47-0
TC-E 5002

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; dichloromethane; at 20 ℃; for 16h;
DOI:10.1021/jm400624b

Reference yield: 13.0%

: 1453071-47-0
TC-E 5002

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 13h; Cooling with ice;

Reference yield:

: 50530-09-1
9-bromononanoic acid sodium salt

: 1453071-47-0
TC-E 5002

Guidance literature:: Multi-step reaction with 4 steps

1.1: dilithium tetrachlorocuprate / tetrahydrofuran / 2 h / -10 °C

1.2: Acidic conditions

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 15 h / 80 °C

3.1: 5%-palladium/activated carbon; hydrogen; ethyl acetate / 1 h / 20 °C

4.1: hydrogenchloride; water / 1,4-dioxane; dichloromethane / 16 h / 20 °C

With hydrogenchloride; dilithium tetrachlorocuprate; 5%-palladium/activated carbon; water; hydrogen; benzotriazol-1-ol; ethyl acetate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm400624b