Technology Process of (2S,3S,4S,5S)-2,5-bis(acetoxymethyl)-1-(benzyloxycarbonyl)piperidine-3,4,5-triyl triacetate
There total 10 articles about (2S,3S,4S,5S)-2,5-bis(acetoxymethyl)-1-(benzyloxycarbonyl)piperidine-3,4,5-triyl triacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/ejoc.201402142
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium periodate / methanol; water / 0.92 - 1 h / 0 °C / Inert atmosphere
2: sodium tetrahydroborate / methanol / 2 h / 0 - 20 °C / Inert atmosphere
3: triethylamine; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere
4: water; sodium periodate; ruthenium(III) chloride trihydrate / ethyl acetate / 0.5 h / 0 - 20 °C / Inert atmosphere
5: triethylamine; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere
With
dmap; sodium tetrahydroborate; sodium periodate; ruthenium(III) chloride trihydrate; water; triethylamine;
In
methanol; dichloromethane; water; ethyl acetate;
DOI:10.1002/ejoc.201402142
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere
2: water; sodium periodate; ruthenium(III) chloride trihydrate / ethyl acetate / 0.5 h / 0 - 20 °C / Inert atmosphere
3: triethylamine; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere
With
dmap; sodium periodate; ruthenium(III) chloride trihydrate; water; triethylamine;
In
dichloromethane; ethyl acetate;
DOI:10.1002/ejoc.201402142
