4-Methoxy-6h-benzo[c]chromen-6-one

Base Information

• Chemical Name: 4-Methoxy-6h-benzo[c]chromen-6-one
• CAS No.: 39597-28-9
• Molecular Formula: C₁₄H₁₀O₃
• Molecular Weight: 226.232
• NSC Number: 134563
• DSSTox Substance ID: DTXSID00300072
• Wikidata: Q82042863

Synonyms:4-methoxy-6h-benzo[c]chromen-6-one;39597-28-9;NSC134563;DTXSID00300072;NSC-134563

Chemical Property of 4-Methoxy-6h-benzo[c]chromen-6-one

Chemical Property:

• Vapor Pressure: 1.38E-06mmHg at 25°C
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 226.062994177
• Heavy Atom Count: 17
• Complexity: 302

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC2=C1OC(=O)C3=CC=CC=C23

Technology Process of 4-Methoxy-6h-benzo[c]chromen-6-one

There total 15 articles about 4-Methoxy-6h-benzo[c]chromen-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

3'-methoxy-[1,1'-biphenyl]-2-carboxylic acid (38087-96-6) → 2-Methoxy-6H-dibenzopyran-6-one (3701-38-0) + 4-methoxy-6H-benzo[c]chromen-6-one (39597-28-9)

Guidance literature:

With tert.-butylnitrite; oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-ethane; at 20 ℃; for 48h; under 750.075 Torr; Irradiation; Sealed tube; Green chemistry;

DOI:10.1055/s-0039-1691537

Reference yield: 54.0%

2-bromo-benzoic acid 2-methoxy-phenyl ester → 4-methoxy-6H-benzo[c]chromen-6-one (39597-28-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2h; Inert atmosphere; Sealed tube; Microwave irradiation; Green chemistry;

DOI:10.1021/acs.joc.8b00048

Reference yield:

3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) → 2-Methoxy-6H-dibenzopyran-6-one (3701-38-0) + 4-methoxy-6H-benzo[c]chromen-6-one (39597-28-9)

Guidance literature:

Multi-step reaction with 3 steps

1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 12 h / 80 °C / Inert atmosphere

2: sodium hydroxide; water / methanol / 12 h / 50 °C / Inert atmosphere

3: 9-(2-mesityl)-10-methylacridinium perchlorate; ammonium peroxydisulfate / water; acetonitrile / 48 h / 20 - 35 °C / Irradiation

With bis-triphenylphosphine-palladium(II) chloride; ammonium peroxydisulfate; water; sodium carbonate; sodium hydroxide; 9-(2-mesityl)-10-methylacridinium perchlorate; In tetrahydrofuran; methanol; water; acetonitrile; 1: |Suzuki Coupling;

DOI:10.1021/acs.orglett.5b02269

upstream raw materials:

diazomethane

4-hydroxy-benzo[c]chromen-6-one

2'-Hydroxy-3'-methoxy-biphenyl-2-carboxylic acid diethylamide

Diethyl-carbamic acid 3-methoxy-biphenyl-2-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 39597-28-9 4-methoxy-6H-benzo[c]chromen-6-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send