Propargyl-PEG5-NHS ester

Base Information

• Chemical Name: Propargyl-PEG5-NHS ester
• CAS No.: 1393330-40-9
• Molecular Formula: C₁₈H₂₇NO₉
• Molecular Weight: 401.414
• Mol file: 1393330-40-9.mol

Synonyms:

Chemical Property of Propargyl-PEG5-NHS ester

Chemical Property:

• Boiling Point: 497.6±55.0 °C(Predicted)
• Density: 1.23±0.1 g/cm3(Predicted)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propargyl-PEG5-NHS Ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Propargyl-PEG5-NHS ester has a propargyl group and an NHS ester group. The terminal NHS ester and is an amine reactive moeity which is useful for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can participate in Click Chemistry reactions with azide compounds, copper is needed for catalyzation. The PEG units can enhance the hydrophilicity of the molecule.

Technology Process of Propargyl-PEG5-NHS ester

There total 1 articles about Propargyl-PEG5-NHS ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,7,10,13,16‐pentaoxanonadec‐18‐ynoic acid (1245823-51-1,1421676-62-1) + O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate (105832-38-0) → propargyl-PEG5-NHS ester (1393330-40-9)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.5h;

upstream raw materials:

4,7,10,13,16‐pentaoxanonadec‐18‐ynoic acid

O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate