(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Base Information

• Chemical Name: (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
• CAS No.: 59779-99-6
• Molecular Formula: C₃₉H₃₇N₃O₇S₂
• Molecular Weight: 723.871

Synonyms:

Chemical Property of (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

There total 2 articles about (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3,5ξ,8-trioxo-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]octane-2ξ-carboxylic acid benzhydryl ester (110131-48-1) → (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester (59779-99-6)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Py, (ii) aq. MCPBA, CH₂Cl₂

2: iPr₂EtN / dimethylformamide

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19750580824

Reference yield:

thiophenol (108-98-5) + (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-(toluene-4-sulfonyloxy)-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester (59779-98-5) → (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester (59779-99-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19750580824

Reference yield:

(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester (59779-99-6) → (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-8-oxo-3-phenylsulfanyl-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester (58232-70-5)

Guidance literature:

With phosphorus trichloride; In dichloromethane; N,N-dimethyl acetamide;

DOI:10.1002/hlca.19750580824

upstream raw materials:

thiophenol

(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-(toluene-4-sulfonyloxy)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3,5ξ,8-trioxo-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]octane-2ξ-carboxylic acid benzhydryl ester

Downstream raw materials:

(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-8-oxo-3-phenylsulfanyl-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

(6R)-7t-((R)-2-amino-2-phenyl-acetylamino)-8-oxo-3-phenylsulfanyl-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 59779-99-6 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-5ξ,8-dioxo-3-phenylsulfanyl-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send