Silane, (2-azido-2-phenylethoxy)trimethyl-

Base Information

• Chemical Name: Silane, (2-azido-2-phenylethoxy)trimethyl-
• CAS No.: 105256-36-8
• Molecular Formula: C11H17N3OSi
• Molecular Weight: 235.361
• DSSTox Substance ID: DTXSID50447729
• Nikkaji Number: J2.879.491F
• Mol file: 105256-36-8.mol

Synonyms:Silane, (2-azido-2-phenylethoxy)trimethyl-;105256-36-8;DTXSID50447729;1-Azido-2-(trimethylsiloxy)ethylbenzene

Chemical Property of Silane, (2-azido-2-phenylethoxy)trimethyl-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 235.114088709
• Heavy Atom Count: 16
• Complexity: 252

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)OCC(C1=CC=CC=C1)N=[N+]=[N-]

Technology Process of Silane, (2-azido-2-phenylethoxy)trimethyl-

There total 3 articles about Silane, (2-azido-2-phenylethoxy)trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

styrene oxide (96-09-3) + trimethylsilylazide (4648-54-8) → 1-azido-1-phenyl-2-(trimethylsilyloxy)ethane (105256-36-8)

Guidance literature:

With erbium(III) triflate; at 0 - 20 ℃; for 0.5h; regioselective reaction;

DOI:10.1016/j.tetlet.2010.07.123

Reference yield: 63.0%

styrene oxide (96-09-3) + trimethylsilylazide (4648-54-8) → 2-azido-1-phenyl-1-(trimethylsilyloxy)ethane (55848-60-7) + 1-azido-1-phenyl-2-(trimethylsilyloxy)ethane (105256-36-8)

Guidance literature:

tetraphenylstibonium hydroxide; In benzene; at 80 ℃; for 24h;

DOI:10.1016/00404-0399(50)09105-

Reference yield:

styrene oxide (96-09-3) + trimethylsilylazide → 2-azido-1-phenyl-1-(trimethylsilyloxy)ethane (55848-60-7) + 2-azido-1-phenylethan-1-ol (124718-87-2,18756-01-9) + 2-azido-2-phenylethanol (124718-93-0) + 1-azido-1-phenyl-2-(trimethylsilyloxy)ethane (105256-36-8)

Guidance literature:

With UMCM-1-AMInpz catalyst; In chloroform-d1; at 20 ℃; for 24h;

DOI:10.1021/ic101125m

upstream raw materials:

styrene oxide

trimethylsilylazide

Downstream raw materials:

2-azido-2-phenylethanol

1-acetoxy-2-azido-2-phenyl ethane

Phenylglycinol