diethyl o-(2-methoxyethoxy)phenyl ortoformate

Base Information

• Chemical Name: diethyl o-(2-methoxyethoxy)phenyl ortoformate
• CAS No.: 74734-01-3
• Molecular Formula: C₁₄H₂₂O₅
• Molecular Weight: 270.326
• Mol file: 74734-01-3.mol

Synonyms:

Chemical Property of diethyl o-(2-methoxyethoxy)phenyl ortoformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl o-(2-methoxyethoxy)phenyl ortoformate

There total 2 articles about diethyl o-(2-methoxyethoxy)phenyl ortoformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

2-(2'-methoxyethoxy)phenol (33130-23-3) + orthoformic acid triethyl ester (122-51-0) → diethyl o-(2-methoxyethoxy)phenyl ortoformate (74734-01-3)

Guidance literature:

With hydrogenchloride; In ethanol; at 130 ℃;

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → diethyl o-(2-methoxyethoxy)phenyl ortoformate (74734-01-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent Turnov_. / sodium methoxide / 1.) 4 h, refux, 2.) overnight, room temperature

2: 21 percent / hydrogen chloride / ethanol / 130 °C

With hydrogenchloride; sodium methylate; In ethanol;

Reference yield:

sec-butylmagnesium bromide (671795-46-3) + diethyl o-(2-methoxyethoxy)phenyl ortoformate (74734-01-3) → 1,1-diethoxy-2-methylbutane (3658-94-4)

Guidance literature:

In tetrahydrofuran; for 0.5h; Heating;

upstream raw materials:

2-(2'-methoxyethoxy)phenol

orthoformic acid triethyl ester

benzene-1,2-diol

Downstream raw materials:

1,1-diethoxy-2-methylbutane