2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid

Base Information

• Chemical Name: 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid
• CAS No.: 107942-09-6
• Molecular Formula: C₂₀H₂₂N₂O₅
• Molecular Weight: 370.405

Synonyms:

Chemical Property of 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid

There total 2 articles about 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyloxycarbonyl-L-α-vinylglycine methyl ester (75266-40-9) → 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid (107942-09-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / molecular sieves / benzene / 12 h / 85 °C

2: 518 mg / 0.56 N LiOH / tetrahydrofuran / 2 h / 5 °C

With lithium hydroxide; molecular sieve; In tetrahydrofuran; benzene;

DOI:10.1021/jo00387a012

Reference yield:

N-benzyl hydroxylalmine (622-30-0) → 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid (107942-09-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / molecular sieves / benzene / 12 h / 85 °C

2: 518 mg / 0.56 N LiOH / tetrahydrofuran / 2 h / 5 °C

With lithium hydroxide; molecular sieve; In tetrahydrofuran; benzene;

DOI:10.1021/jo00387a012

Reference yield: 73.0%

2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid (107942-09-6) → treo-N5-benzyl-β-hydroxy-L-ornithine hydrochloride (107942-11-0)

Guidance literature:

With ammonia; sodium; for 3h;

DOI:10.1021/jo00387a012

upstream raw materials:

N-benzyloxycarbonyl-L-α-vinylglycine methyl ester

N-benzyl hydroxylalmine

Downstream raw materials:

treo-N⁵-benzyl-β-hydroxy-L-ornithine hydrochloride

(3R)-hydroxy-(2S)-ornithine hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 107942-09-6 2(S)-<2-benzyl-5(S)-isoxazolidynyl>acetic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send