Se-phenyl 5-ethoxyselenohept-6-enoate

Base Information

• Chemical Name: Se-phenyl 5-ethoxyselenohept-6-enoate
• CAS No.: 119124-38-8
• Molecular Formula: C₁₅H₂₀O₂Se
• Molecular Weight: 311.283
• Mol file: 119124-38-8.mol

Synonyms:

Chemical Property of Se-phenyl 5-ethoxyselenohept-6-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Se-phenyl 5-ethoxyselenohept-6-enoate

There total 6 articles about Se-phenyl 5-ethoxyselenohept-6-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 1,1-diethoxypropane-3,3-dicarboxylate (92320-33-7) → Se-phenyl 5-ethoxyselenohept-6-enoate (119124-38-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 83 percent / titanium tetrachloride / CH₂Cl₂ / 0.5 h / -78 °C

2: 55 percent / lithium chloride / dimethylsulfoxide; H₂O / 15 h / 150 °C

3: 93 percent / hydrogen / Lindlaar's catalyst poisoned with quinoline / ethanol / 9 h

4: 99 percent / potassium hydroxide / methanol; H₂O

5: 1.) sodium hydrogen carbonate, water; 2.) oxalyl chloride / 1.) benzene, 60 deg C; 2.) r.t., 1 h

6: 1.) sodium borohydride / 1.) ethanol, 0 deg C; 2.) ethanol, r.t., 30 h

With potassium hydroxide; sodium tetrahydroborate; oxalyl dichloride; water; hydrogen; titanium tetrachloride; sodium hydrogencarbonate; lithium chloride; Lindlar's catalyst poisoned with quinoline; In methanol; ethanol; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1016/S0040-4020(01)89534-X

Reference yield:

ethyl 2-carboethoxy-5-ethoxy-7-trimethylsilylhept-6-ynoate (127392-36-3) → Se-phenyl 5-ethoxyselenohept-6-enoate (119124-38-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 55 percent / lithium chloride / dimethylsulfoxide; H₂O / 15 h / 150 °C

2: 93 percent / hydrogen / Lindlaar's catalyst poisoned with quinoline / ethanol / 9 h

3: 99 percent / potassium hydroxide / methanol; H₂O

4: 1.) sodium hydrogen carbonate, water; 2.) oxalyl chloride / 1.) benzene, 60 deg C; 2.) r.t., 1 h

5: 1.) sodium borohydride / 1.) ethanol, 0 deg C; 2.) ethanol, r.t., 30 h

With potassium hydroxide; sodium tetrahydroborate; oxalyl dichloride; water; hydrogen; sodium hydrogencarbonate; lithium chloride; Lindlar's catalyst poisoned with quinoline; In methanol; ethanol; water; dimethyl sulfoxide;

DOI:10.1016/S0040-4020(01)89534-X

Reference yield:

ethyl 5-ethoxyhept-6-ynoate (127392-37-4) → Se-phenyl 5-ethoxyselenohept-6-enoate (119124-38-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / hydrogen / Lindlaar's catalyst poisoned with quinoline / ethanol / 9 h

2: 99 percent / potassium hydroxide / methanol; H₂O

3: 1.) sodium hydrogen carbonate, water; 2.) oxalyl chloride / 1.) benzene, 60 deg C; 2.) r.t., 1 h

4: 1.) sodium borohydride / 1.) ethanol, 0 deg C; 2.) ethanol, r.t., 30 h

With potassium hydroxide; sodium tetrahydroborate; oxalyl dichloride; water; hydrogen; sodium hydrogencarbonate; Lindlar's catalyst poisoned with quinoline; In methanol; ethanol; water;

DOI:10.1016/S0040-4020(01)89534-X

upstream raw materials:

diphenyl diselenide

diethyl 1,1-diethoxypropane-3,3-dicarboxylate

5-ethoxyhept-6-enoic acid

ethyl 5-ethoxyhept-6-ynoate