N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide

Base Information

• Chemical Name: N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide
• CAS No.: 91880-24-9
• Molecular Formula: C₂₉H₃₉NO₆S₂
• Molecular Weight: 561.764
• Mol file: 91880-24-9.mol

Synonyms:

Chemical Property of N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide

There total 10 articles about N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(p-toluenesulfonyl)aziridine (3634-89-7) → N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide (91880-24-9)

Guidance literature:

Multi-step reaction with 10 steps

3: aq.HCl

6: m-chloroperbenzoic acid

7: diisobutylaluminum hydride

9: various solvent(s)

10: 1) n-BuLi / 1) THF / -78 deg C / 30 min, 2) quenching

With hydrogenchloride; n-butyllithium; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; In various solvent(s);

DOI:10.1021/jo00194a051

Reference yield:

N-[2-(2,6-Dioxo-cyclohexyl)-ethyl]-4,N-dimethyl-benzenesulfonamide → N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide (91880-24-9)

Guidance literature:

Multi-step reaction with 7 steps

3: m-chloroperbenzoic acid

4: diisobutylaluminum hydride

6: various solvent(s)

7: 1) n-BuLi / 1) THF / -78 deg C / 30 min, 2) quenching

With n-butyllithium; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; In various solvent(s);

DOI:10.1021/jo00194a051

Reference yield:

N-[2-(2,6-Dimethoxy-cyclohexa-2,4-dienyl)-ethyl]-4-methyl-benzenesulfonamide → N-{2-[2-(2-Methoxy-5-vinyl-phenoxy)-6-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide (91880-24-9)

Guidance literature:

Multi-step reaction with 9 steps

2: aq.HCl

5: m-chloroperbenzoic acid

6: diisobutylaluminum hydride

8: various solvent(s)

9: 1) n-BuLi / 1) THF / -78 deg C / 30 min, 2) quenching

With hydrogenchloride; n-butyllithium; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; In various solvent(s);

DOI:10.1021/jo00194a051

upstream raw materials:

N-{2-[6-(2-Bromo-6-methoxy-3-vinyl-phenoxy)-2-(2-methyl-propane-2-sulfonyl)-cyclohex-1-enyl]-ethyl}-4,N-dimethyl-benzenesulfonamide

N-(p-toluenesulfonyl)aziridine

N-[2-(2-tert-Butylsulfanyl-6-oxo-cyclohex-1-enyl)-ethyl]-4,N-dimethyl-benzenesulfonamide

4,N-Dimethyl-N-{2-[2-(2-methyl-propane-2-sulfonyl)-6-oxo-cyclohex-1-enyl]-ethyl}-benzenesulfonamide