1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene

Base Information

• Chemical Name: 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene
• CAS No.: 1209481-43-5
• Molecular Formula: C₃₃H₆₀N₆
• Molecular Weight: 540.88
• Mol file: 1209481-43-5.mol

Synonyms:

Chemical Property of 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene

There total 4 articles about 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3,5-tris[methyl-(tert-butoxycarbonyl-trans-1,2-diaminocyclohexyl)]-2,4,6-triethylbenzene (1209481-28-6) → 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene (1209481-43-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere;

DOI:10.1002/chem.201002871

Reference yield:

C48H78N6O6 → 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene (1209481-43-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol; chloroform / 1 h / 20 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; trifluoroacetic acid; In methanol; dichloromethane; chloroform;

DOI:10.1002/chem.201002871

Reference yield:

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene (181058-08-2) → 1,3,5-tris{[(trans-2'-aminocyclohexyl)amino]methyl}-2,4,6-triethylbenzene (1209481-43-5)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium dichromate / Inert atmosphere

2: methanol; chloroform / 7.5 h / 70 °C / Inert atmosphere

3: sodium tetrahydroborate / methanol; chloroform / 1 h / 20 °C / Inert atmosphere

4: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

With potassium dichromate; sodium tetrahydroborate; trifluoroacetic acid; In methanol; dichloromethane; chloroform;

DOI:10.1002/chem.201002871

upstream raw materials:

1,3,5-tris[methyl-(tert-butoxycarbonyl-trans-1,2-diaminocyclohexyl)]-2,4,6-triethylbenzene

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene

2,4,6-triethylbenzene-1,3,5-tricarbaldehyde

Downstream raw materials:

CN₁₉_17

C₄₄H₇₀N₈

1,3,5-tris{[(trans-2'-{[1H-pyrrol-2-ylmethyl]amino}cyclohexyl)amino]methyl}-2,4,6-triethylbenzene