9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran

Base Information

• Chemical Name: 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran
• CAS No.: 1353573-09-7
• Molecular Formula: C₃₁H₂₀O₅
• Molecular Weight: 472.497
• Mol file: 1353573-09-7.mol

Synonyms:

Chemical Property of 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran

There total 2 articles about 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

9'-methoxy-3'-bromobenzo[a]fluoran (1353573-01-9) + 3-hydroxyphenylboronic acid (87199-18-6) → 9'-methoxybenzo[a]fluoran (1353573-03-1) + 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran (1353573-09-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; toluene; for 22h; Reflux; Inert atmosphere;

DOI:10.1039/c1cc15854f

Reference yield:

6-bromo-naphthalen-2-ol (15231-91-1) + phthalic anhydride (85-44-9) + 1,3-Dimethoxybenzene (151-10-0) → 9'-methoxybenzo[a]fluoran (1353573-03-1) + 9'-methoxy-3'-(3-hydroxyphenyl)benzo[a]fluoran (1353573-09-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / dichloromethane / 0.33 h / 20 °C

1.2: 20 h / 20 °C

1.3: 16 h / 50 °C

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / ethanol; toluene / 22 h / Reflux; Inert atmosphere

With aluminum (III) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; dichloromethane; toluene; 2.1: Suzuki coupling;

DOI:10.1039/c1cc15854f

upstream raw materials:

6-bromo-naphthalen-2-ol

phthalic anhydride

1,3-Dimethoxybenzene

9'-methoxy-3'-bromobenzo[a]fluoran