C₃₁H₃₄O₅

Base Information

• Chemical Name: C₃₁H₃₄O₅
• CAS No.: 288578-85-8
• Molecular Formula: C₃₁H₃₄O₅
• Molecular Weight: 486.608
• Mol file: 288578-85-8.mol

Synonyms:

Chemical Property of C₃₁H₃₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₄O₅

There total 6 articles about C₃₁H₃₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C31H36O5 (288578-84-7) → C31H34O5 (288578-85-8)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(00)00508-6

Reference yield:

(1S,2R,3R,4R)-2-(tert-butyldiphenylsilyloxymethyl)-3-(formylmethyl)-1,4-bis-O-(triethylsilyl)cyclopentane-1,4-diol (213777-19-6) → C31H34O5 (288578-85-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 68 percent / sodium hexamethyldisilyl amide / tetrahydrofuran / 2 h / -80 - 20 °C

2: 92 percent / ammonium fluoride / methanol; tetrahydrofuran / 4 h / 60 °C

3: 86 percent / pyridine / 1 h / 20 °C

4: 73 percent / aq. hydrogen chloride / methanol; diethyl ether / 20 °C

5: periodinane / CH₂Cl₂ / 2 h / 20 °C

With pyridine; hydrogenchloride; ammonium fluoride; sodium hexamethyldisilazane; Dess-Martin periodane; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; 1: Condensation / 2: desilylation / 3: Esterification / 4: Hydrolysis / 5: Oxidation;

DOI:10.1016/S0040-4039(00)00508-6

Reference yield:

(1S,2S,3R,4R)-1,4-Bis(triethylsilyloxy)-3-(methoxycarbonylmethyl)-2-tert-butyldiphenylsilyloxymethylcyclopentane (213777-18-5) → C31H34O5 (288578-85-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 93 percent / DIBAL-H / toluene / 0.5 h / -80 °C

2: 68 percent / sodium hexamethyldisilyl amide / tetrahydrofuran / 2 h / -80 - 20 °C

3: 92 percent / ammonium fluoride / methanol; tetrahydrofuran / 4 h / 60 °C

4: 86 percent / pyridine / 1 h / 20 °C

5: 73 percent / aq. hydrogen chloride / methanol; diethyl ether / 20 °C

6: periodinane / CH₂Cl₂ / 2 h / 20 °C

With pyridine; hydrogenchloride; ammonium fluoride; sodium hexamethyldisilazane; diisobutylaluminium hydride; Dess-Martin periodane; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; 1: Reduction / 2: Condensation / 3: desilylation / 4: Esterification / 5: Hydrolysis / 6: Oxidation;

DOI:10.1016/S0040-4039(00)00508-6

upstream raw materials:

C₃₁H₃₆O₅

(1S,2R,3R,4R)-2-(tert-butyldiphenylsilyloxymethyl)-3-(formylmethyl)-1,4-bis-O-(triethylsilyl)cyclopentane-1,4-diol

(1S,2S,3R,4R)-1,4-Bis(triethylsilyloxy)-3-(methoxycarbonylmethyl)-2-tert-butyldiphenylsilyloxymethylcyclopentane

(1R,3S,4R,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-((2Z,5Z,8Z)-undeca-2,5,8-trienyl)-cyclopentane-1,3-diol

Downstream raw materials:

C₃₆H₄₀O₆

C₃₇H₄₂O₇