3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one

Base Information

Chemical Name:3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one
CAS No.:84023-76-7
Molecular Formula:C19H16 O4
Molecular Weight:308.334
Hs Code.:
NSC Number:138933

Synonyms:84023-76-7;2(3H)-Furanone,3-[(3,4-dimethoxyphenyl)methylene]-5-phenyl-;NSC138933;3-(3,4-DIMETHOXY-BENZYLIDENE)-5-PHENYL-3H-FURAN-2-ONE;(3Z)-3-[(3,4-dimethoxyphenyl)methylidene]-5-phenyl-2,3-dihydrofuran-2-one;AKOS001608537;NSC-138933;AB00090885-01;SR-01000408815;SR-01000408815-1

Suppliers and Price of 3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one

Chemical Property:

Vapor Pressure:1.54E-11mmHg at 25°C
Boiling Point:535.4°C at 760 mmHg
Flash Point:238.3°C
Density:1.245g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:308.10485899
Heavy Atom Count:23
Complexity:488

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C=C2C=C(OC2=O)C3=CC=CC=C3)OC
Isomeric SMILES:COC1=C(C=C(C=C1)/C=C\2/C=C(OC2=O)C3=CC=CC=C3)OC

Technology Process of 3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one

There total 4 articles about 3-(3,4-Dimethoxy-benzylidene)-5-phenyl-3H-furan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 2051-95-8
succinylbenzene

: 84023-76-7
(3,4-dimethoxybenzylidene)γ-phenyl-δ,β-butenolide

Guidance literature:: With pyridine; acetic anhydride; for 0.25h; Microwave irradiation;

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 84023-76-7
(3,4-dimethoxybenzylidene)γ-phenyl-δ,β-butenolide

Guidance literature:: With acetic anhydride;
DOI:10.1039/jr9590001020 DOI:10.1039/jr9360000587

Reference yield:

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 84023-76-7
(3,4-dimethoxybenzylidene)γ-phenyl-δ,β-butenolide

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / 0.5 h / Reflux

2: triethylamine; acetic anhydride / 0.25 h / Heating

With aluminum (III) chloride; acetic anhydride; triethylamine; 1: |Friedel-Crafts Acylation;
DOI:10.1016/j.bioorg.2020.104522