3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine

Base Information

Chemical Name:3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine
CAS No.:81411-65-6
Molecular Formula:C₇H₇N₅O
Molecular Weight:177.165
Hs Code.:
DSSTox Substance ID:DTXSID601238179

Synonyms:81411-65-6;3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine;DTXSID601238179

Suppliers and Price of 3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine

Chemical Property:

XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:177.06505986
Heavy Atom Count:13
Complexity:178

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=NO1)C2=NC=CN=C2N

Technology Process of 3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine

There total 1 articles about 3-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-pyrazinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 85124-02-3
2-aminopyrazine-3-carboxamide O-(1,1-diethoxy)ethyloxime

: 76952-35-7
2-aminopyrazine-3-carboxamide oxime

: 76952-47-1
4-amino-2-methylpteridine-3-oxide

: 81411-65-6
2-amino-3-(5'-methyl-1',2',4'-oxadiazolyl-3')pyrazine

Guidance literature:: With acetic acid; for 0.833333h; Heating;

Reference yield:

: 81411-65-6
2-amino-3-(5'-methyl-1',2',4'-oxadiazolyl-3')pyrazine

: 81411-63-4
3-benzoylamino-1H-pyrazolo(3,4-b)pyrazine

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / NaOH / dimethylformamide / 1 h / Heating

2: 36 percent / 10percent aq. NaOH / 1 h / Heating

3: 10 percent / pyridine / 2 h / Heating

With sodium hydroxide; In pyridine; N,N-dimethyl-formamide;
DOI:10.1007/BF00809014

Reference yield:

: 81411-65-6
2-amino-3-(5'-methyl-1',2',4'-oxadiazolyl-3')pyrazine

: 81411-70-3
5,5-Dimethyl-2-[(1H-pyrazolo[3,4-b]pyrazin-3-yl)-hydrazono]-cyclohexane-1,3-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 68 percent / NaOH / dimethylformamide / 1 h / Heating

2: 36 percent / 10percent aq. NaOH / 1 h / Heating

3: 43 percent / conc. HCl, NaNO₂ / H₂O / 0.33 h / Ambient temperature

4: 73 percent / ethanol / 8 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; sodium nitrite; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1007/BF00809014