C₄₆H₅₀N₄O₁₀P₂S₄

Base Information

• Chemical Name: C₄₆H₅₀N₄O₁₀P₂S₄
• CAS No.: 906552-50-9
• Molecular Formula: C₄₆H₅₀N₄O₁₀P₂S₄
• Molecular Weight: 1009.14
• Mol file: 906552-50-9.mol

Synonyms:

Chemical Property of C₄₆H₅₀N₄O₁₀P₂S₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₆H₅₀N₄O₁₀P₂S₄

There total 5 articles about C₄₆H₅₀N₄O₁₀P₂S₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-(2',3'-O-isopropylidene-4',5'-di-O-acetyl-D-ribityl)hypoxanthine (1067074-02-5) → C46H50N4O10P2S4 (906552-50-9)

Guidance literature:

Multi-step reaction with 4 steps

1: ammonium nitrate; trifluoroacetic anhydride / CH₂Cl₂ / 0 °C

2: dimethylformamide / 8 h / 20 °C

3: K₂CO₃; MeOH / 0.25 h / 20 °C

4: 2,4,6-triisopropylbenzenesulfonyl chloride; tetrazole; pyridine / 8 h / 20 °C

With pyridine; 1H-tetrazole; methanol; 2,4,6-triisopropylphenylsulfonyl chloride; ammonium nitrate; potassium carbonate; trifluoroacetic anhydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1081/NCN-200060041

Reference yield:

acetic acid 2-acetoxy-1-[2,2-dimethyl-5-(1-nitro-6-oxo-1,6-dihydro-purin-9-ylmethyl)-[1,3]dioxolan-4-yl]-ethyl ester (1067074-03-6) → C46H50N4O10P2S4 (906552-50-9)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylformamide / 8 h / 20 °C

2: K₂CO₃; MeOH / 0.25 h / 20 °C

3: 2,4,6-triisopropylbenzenesulfonyl chloride; tetrazole; pyridine / 8 h / 20 °C

With pyridine; 1H-tetrazole; methanol; 2,4,6-triisopropylphenylsulfonyl chloride; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1081/NCN-200060041

Reference yield:

9-[(4S,5R)-5-((R)-1,2-Dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-1,9-dihydro-purin-6-one (151359-34-1) → C46H50N4O10P2S4 (906552-50-9)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine / 20 °C

2: ammonium nitrate; trifluoroacetic anhydride / CH₂Cl₂ / 0 °C

3: dimethylformamide / 8 h / 20 °C

4: K₂CO₃; MeOH / 0.25 h / 20 °C

5: 2,4,6-triisopropylbenzenesulfonyl chloride; tetrazole; pyridine / 8 h / 20 °C

With pyridine; 1H-tetrazole; methanol; 2,4,6-triisopropylphenylsulfonyl chloride; ammonium nitrate; potassium carbonate; trifluoroacetic anhydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1081/NCN-200060041

upstream raw materials:

cyclohexylammonium S,S-diphenyl phosphorodithioate

9-(2',3'-O-isopropylidene-4',5'-di-O-acetyl-D-ribityl)hypoxanthine

acetic acid 2-acetoxy-1-[2,2-dimethyl-5-(1-nitro-6-oxo-1,6-dihydro-purin-9-ylmethyl)-[1,3]dioxolan-4-yl]-ethyl ester

9-[(4S,5R)-5-((R)-1,2-Dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-1,9-dihydro-purin-6-one