C₂₅H₁₈BrN₇O₃S

Base Information

• Chemical Name: C₂₅H₁₈BrN₇O₃S
• CAS No.: 1380517-64-5
• Molecular Formula: C₂₅H₁₈BrN₇O₃S
• Molecular Weight: 576.433
• Mol file: 1380517-64-5.mol

Synonyms:

Chemical Property of C₂₅H₁₈BrN₇O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₁₈BrN₇O₃S

There total 10 articles about C₂₅H₁₈BrN₇O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C25H18BrN7OS (1380517-56-5) → C25H18BrN7O3S (1380517-64-5)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 100 ℃; for 6h; water bath;

DOI:10.1080/10426507.2011.643433

Reference yield:

6-bromo-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide (1268872-15-6) → C25H18BrN7O3S (1380517-64-5)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol / Reflux

2: sodium hydroxide / 1 h / 100 °C

3: potassium carbonate / N,N-dimethyl-formamide / 2 h / 120 °C / Temperature controlled oil-bath

4: dihydrogen peroxide; acetic acid / 6 h / 100 °C / water bath

With dihydrogen peroxide; potassium carbonate; acetic acid; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1080/10426507.2011.643433

Reference yield:

ethyl 6-bromo-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate → C25H18BrN7O3S (1380517-64-5)

Guidance literature:

Multi-step reaction with 5 steps

1: hydrazine hydrate / ethanol / 3 h

2: ethanol / Reflux

3: sodium hydroxide / 1 h / 100 °C

4: potassium carbonate / N,N-dimethyl-formamide / 2 h / 120 °C / Temperature controlled oil-bath

5: dihydrogen peroxide; acetic acid / 6 h / 100 °C / water bath

With dihydrogen peroxide; potassium carbonate; hydrazine hydrate; acetic acid; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1080/10426507.2011.643433

upstream raw materials:

2-chloromethyl-1H-benzimidazole

C₁₇H₁₂BrN₅OS

C₁₇H₁₄BrN₅O₂S

C₁₉H₁₄BrN₅O₃S