Technology Process of C22H20N4O
There total 5 articles about C22H20N4O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: (2’,4’,6’-triisopropyl-[1,1’-biphenyl]-2-yl)-diphenylphosphine; 2-methyltetrahydrofuran; palladium diacetate; caesium carbonate / 1 h / 100 °C / Microwave irradiation; Inert atmosphere
2: diisobutylaluminium hydride / dichloromethane / 1.5 h / -78 °C
3: acetic acid; zinc / 2 h / 20 °C
With
(2’,4’,6’-triisopropyl-[1,1’-biphenyl]-2-yl)-diphenylphosphine; 2-methyltetrahydrofuran; palladium diacetate; diisobutylaluminium hydride; caesium carbonate; acetic acid; zinc;
In
dichloromethane;
1: Suzuki coupling;
DOI:10.1021/jo202467k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diisobutylaluminium hydride / dichloromethane / 1.5 h / -78 °C
2: acetic acid; zinc / 2 h / 20 °C
With
diisobutylaluminium hydride; acetic acid; zinc;
In
dichloromethane;
DOI:10.1021/jo202467k