C₁₈H₁₈BrN

Base Information

• Chemical Name: C₁₈H₁₈BrN
• CAS No.: 1429926-48-6
• Molecular Formula: C₁₈H₁₈BrN
• Molecular Weight: 328.252
• Mol file: 1429926-48-6.mol

Synonyms:

Chemical Property of C₁₈H₁₈BrN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₈H₁₈BrN

There total 2 articles about C₁₈H₁₈BrN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-4-(indol-3-yl)-1-phenylbutan-1-ol (1429926-47-5) → C18H18BrN (1429926-48-6)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo400365e

Reference yield:

4-(1H-indol-3-yl)-1-phenylbutan-1-one → C18H18BrN (1429926-48-6)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

2: triphenylphosphine; carbon tetrabromide / dichloromethane / 0 - 20 °C

With lithium aluminium tetrahydride; carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo400365e

Reference yield:

C18H18BrN (1429926-48-6) → C18H17N (1429926-44-2) + C18H17N

Guidance literature:

C₁₈H₁₈BrN; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

Overall yield = 0.15 g; Resolution of racemate;

DOI:10.1021/jo400365e

upstream raw materials:

(±)-4-(indol-3-yl)-1-phenylbutan-1-ol

Downstream raw materials:

C₁₈H₁₇N