C₃₇H₂₉N₁₁O₆

Base Information

• Chemical Name: C₃₇H₂₉N₁₁O₆
• CAS No.: 1359849-39-0
• Molecular Formula: C₃₇H₂₉N₁₁O₆
• Molecular Weight: 723.707
• Mol file: 1359849-39-0.mol

Synonyms:

Chemical Property of C₃₇H₂₉N₁₁O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₂₉N₁₁O₆

There total 14 articles about C₃₇H₂₉N₁₁O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-bis(methoxycarbonyl)pyridine (5453-67-8) → C37H29N11O6 (1359849-39-0)

Guidance literature:

Multi-step reaction with 11 steps

1.1: methanol; potassium hydroxide / 20 °C

2.1: 4-methyl-morpholine; chloroformic acid ethyl ester / tetrahydrofuran; N,N-dimethyl-formamide / -10 - 0 °C

3.1: sodium azide / water

4.1: toluene / Reflux

5.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran

6.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

7.1: sodium hydroxide / 1,4-dioxane / 20 °C

8.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

9.1: sodium hydroxide / 1,4-dioxane; water / 20 °C

10.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C

11.1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

11.2: 20 °C

With 4-methyl-morpholine; methanol; sodium azide; oxalyl dichloride; palladium 10% on activated carbon; hydrogen; chloroformic acid ethyl ester; triethylamine; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 4.1: Curtius rearrangement;

DOI:10.1039/c1ob06609a

Reference yield:

C8H6N4O3 → C37H29N11O6 (1359849-39-0)

Guidance literature:

Multi-step reaction with 10 steps

1.1: toluene / Reflux

2.1: sodium hydroxide / 1,4-dioxane / 20 °C

3.1: 4-methyl-morpholine; chloroformic acid ethyl ester / tetrahydrofuran; N,N-dimethyl-formamide / -10 - 0 °C

4.1: sodium hydroxide / 1,4-dioxane / 20 °C

5.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

6.1: sodium hydroxide / 1,4-dioxane / 20 °C

7.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

8.1: sodium hydroxide / 1,4-dioxane; water / 20 °C

9.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C

10.1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

10.2: 20 °C

With 4-methyl-morpholine; oxalyl dichloride; chloroformic acid ethyl ester; triethylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 1.1: Curtius rearrangement;

DOI:10.1039/c1ob06609a

Reference yield:

methyl 6-(benzyloxycarbonylamino)-pyridine-2-carboxylate (1262043-88-8) → C37H29N11O6 (1359849-39-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran

2.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

3.1: sodium hydroxide / 1,4-dioxane; water / 20 °C

4.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C

5.1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

5.2: 20 °C

With oxalyl dichloride; palladium 10% on activated carbon; hydrogen; triethylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/c1ob06609a

upstream raw materials:

2,6-bis(methoxycarbonyl)pyridine

methyl 6-aminopyridine-2-carboxylate

C₂₁H₁₈N₄O₅

C₂₀H₁₆N₄O₅