3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Base Information

• Chemical Name: 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside
• CAS No.: 1361996-91-9
• Molecular Formula: C₅₇H₆₆O₁₇S
• Molecular Weight: 1055.21

Synonyms:

Chemical Property of 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

There total 8 articles about 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,3-trimethoxybenzene (621-23-8) + 2-(S)-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-β-D-glucopyranoso)[1,2-e]-1,4-oxathiane (S)-S-oxide (1361996-85-1) + methyl 2,3,6-tri-O-benzyl-α-D-mannopyranoside (19488-48-3,19488-49-4,51842-16-1,55697-49-9,115414-37-4,95475-33-5) → 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside (1361996-91-9) + 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-β-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Guidance literature:

1,2,3-trimethoxybenzene; 2-(S)-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-β-D-glucopyranoso)[1,2-e]-1,4-oxathiane (S)-S-oxide; With 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -60 - -10 ℃; for 0.166667h; Inert atmosphere; Molecular sieve;

methyl 2,3,6-tri-O-benzyl-α-D-mannopyranoside; In dichloromethane; at 20 ℃; for 24h; optical yield given as %de; diastereoselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.1002/chem.201101889

Reference yield:

2-(S)-phenyl-(1,2-dideoxy-β-D-glucopyranoso)[1,2-e]-1,4-oxathiane → 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside (1361996-91-9) + 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-β-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Guidance literature:

Multi-step reaction with 3 steps

1.1: pyridine / Inert atmosphere

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.42 h / -78 °C / Inert atmosphere

3.1: 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride / dichloromethane / 0.17 h / -60 - -10 °C / Inert atmosphere; Molecular sieve

3.2: 24 h / 20 °C / Inert atmosphere; Molecular sieve

With pyridine; 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1002/chem.201101889

Reference yield:

2-methoxy-2-(S)-phenyl-(1,2-dideoxy-β-D-glucopyranoso)[1,2-e]-1,4-oxathiane (1197819-98-9) → 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside (1361996-91-9) + 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-β-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Guidance literature:

Multi-step reaction with 4 steps

1.1: triethylsilane; trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / Inert atmosphere

2.1: pyridine / Inert atmosphere

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.42 h / -78 °C / Inert atmosphere

4.1: 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride / dichloromethane / 0.17 h / -60 - -10 °C / Inert atmosphere; Molecular sieve

4.2: 24 h / 20 °C / Inert atmosphere; Molecular sieve

With pyridine; triethylsilane; 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride; trimethylsilyl trifluoromethanesulfonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1002/chem.201101889

upstream raw materials:

C₁₄H₁₈O₆S

2-methoxy-2-(S)-phenyl-(1,2-dideoxy-β-D-glucopyranoso)[1,2-e]-1,4-oxathiane

2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranosyl acetophenone

1,2,3-trimethoxybenzene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1361996-91-9 3,4,6-tri-O-acetyl-2-O-[1-(S)-phenyl-2-(2,4,6-trimethoxyphenylsulfanyl)ethyl]-α-D-glucopyranosyl-(1->4)-methyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send