Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate

Base Information

Chemical Name:Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate
CAS No.:105550-86-5
Molecular Formula:C14H10ClNO5S
Molecular Weight:339.756
Hs Code.:
DSSTox Substance ID:DTXSID10544667
Wikidata:Q82421868

Synonyms:105550-86-5;DTXSID10544667;Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate

Suppliers and Price of Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:338.9968213
Heavy Atom Count:22
Complexity:455

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=CC=C(S1)C(=O)C2=C(C=C(C=C2)[N+](=O)[O-])Cl

Technology Process of Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate

There total 1 articles about Methyl [5-(2-chloro-4-nitrobenzoyl)thiophen-2-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.5%

: 19432-68-9
methyl 2-thiopheneacetate

: 7073-36-1
2-chloro-4-nitrobenzoyl chloride

: 105550-86-5
5-(2-cloro-4-nitrobenzoil)tiofen-2-acetato di metile

Guidance literature:: With aluminium trichloride; In 1,2-dichloro-ethane; 1.) 15 min, r.t; 2.) 15 min, reflux;

Reference yield: 84.1%

: 105550-86-5
5-(2-cloro-4-nitrobenzoil)tiofen-2-acetato di metile

: 105550-89-8
5-(4-ammino-2-clorobenzoil)tiofen-2-acetato di metile

Guidance literature:: With iron; calcium chloride; In ethanol; for 2h; Heating;

Reference yield:

: 105550-86-5
5-(2-cloro-4-nitrobenzoil)tiofen-2-acetato di metile

: 105550-91-2
5-<2-cloro-4-(1H-pirrol-1-il)-benzoil>tiofen-2-acetato di metile

Guidance literature:: Multi-step reaction with 2 steps

1: 84.1 percent / Fe, CaCl₂ / ethanol / 2 h / Heating

2: 72.4 percent / acetic acid / 0.17 h / 120 °C

With iron; calcium chloride; In ethanol; acetic acid;