6-Α-METHYLPREDNISOLONE

Base Information

• Chemical Name: 6-Α-METHYLPREDNISOLONE
• CAS No.: 18462-27-6
• Molecular Formula: C₂₂H₃₀O₅
• Molecular Weight: 374.477
• Mol file: 18462-27-6.mol

Synonyms:

Chemical Property of 6-Α-METHYLPREDNISOLONE

Chemical Property:

Purity/Quality:

> 95% ^*data from raw suppliers

6β-Methylprednisolone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6β-Methylprednisolone, is a glucocorticoid, and is the derivative of Prednisolone (P703740), a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. It is the active metabolite of the drug prednisone.

Technology Process of 6-Α-METHYLPREDNISOLONE

There total 4 articles about 6-Α-METHYLPREDNISOLONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (6S,17R)-11,17-Dihydroxy-17-(2-hydroxy-acetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one (83-43-2,6923-42-8,18462-27-6,105500-05-8)

Guidance literature:

/BRN= 227840/ (XX) 1. OsO4/N-Me-Morpholin-oxid-peroxid 2. KHCO3;

Reference yield:

→ 11β.17α.21-Trihydroxy-3.20-dioxo-6α-methyl-pregnadien-(1.4) (83-43-2,6923-42-8,18462-27-6,105500-05-8)

Guidance literature:

entspr. unmark. Substanz, T2-Gas (Wilzbach-Methode);

DOI:10.1002/jlcr.2590070418

Reference yield:

→ 6β-Methyl-1-dehydro-hydrocortison (83-43-2,6923-42-8,18462-27-6,105500-05-8)

Guidance literature:

6β-Methyl-hydrocortison durch biochem. Dehydrierung mit Septomyxa affinis;