Technology Process of C15H15ClFN5O
There total 2 articles about C15H15ClFN5O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: bromine / water / 2 h / 20 - 100 °C
2: dimethylaminoacetic acid; caesium carbonate; copper(l) iodide / 1,4-dioxane / 120 °C / Inert atmosphere
With
copper(l) iodide; dimethylaminoacetic acid; bromine; caesium carbonate;
In
1,4-dioxane; water;
DOI:10.1021/acs.jmedchem.7b01192
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 3 h / 180 °C
2: bromine / water / 2 h / 20 - 100 °C
3: dimethylaminoacetic acid; caesium carbonate; copper(l) iodide / 1,4-dioxane / 120 °C / Inert atmosphere
With
copper(l) iodide; dimethylaminoacetic acid; bromine; caesium carbonate;
In
1,4-dioxane; water;
DOI:10.1021/acs.jmedchem.7b01192
- Guidance literature:
-
Multi-step reaction with 2 steps
1: formic acid; hydrogenchloride / 2 h / Reflux
2: caesium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
With
hydrogenchloride; formic acid; caesium carbonate;
In
N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b01192