Technology Process of (N-formyl-7-methoxy-6-methyl-5,8-dioxo-1,2,5,8-tetrahydro-1-isoquinolyl)methyl benzoate
There total 13 articles about (N-formyl-7-methoxy-6-methyl-5,8-dioxo-1,2,5,8-tetrahydro-1-isoquinolyl)methyl benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
palladium on activated charcoal;
In
benzene;
for 48h;
Heating;
DOI:10.1248/cpb.34.4056
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 81 percent / hydrogen / platinum (IV) dioxide / acetic acid / 5 h / 760 Torr
2: 95 percent / methanol / 12 h
3: 74 percent / 1.88 M phenyllithium / tetrahydrofuran; benzene / 0.08 h / -40 °C
4: 31 percent / ceric ammonium nitrate (CAN), pyridine-2,6-dicarboxylic acid N-oxide / acetonitrile; H2O / 0.33 h
5: 59 percent / 10percent palladium on carbon / benzene / 48 h / Heating
With
Pyridine-2,6-dicarboxylic acid N-oxide; ammonium cerium(IV) nitrate; hydrogen; phenyllithium;
platinum(IV) oxide; palladium on activated charcoal;
In
tetrahydrofuran; methanol; water; acetic acid; acetonitrile; benzene;
DOI:10.1248/cpb.34.4056
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 93 percent / KOH / methanol / 0.08 h / Heating
2: 81 percent / hydrogen / platinum (IV) dioxide / acetic acid / 5 h / 760 Torr
3: 95 percent / methanol / 12 h
4: 74 percent / 1.88 M phenyllithium / tetrahydrofuran; benzene / 0.08 h / -40 °C
5: 31 percent / ceric ammonium nitrate (CAN), pyridine-2,6-dicarboxylic acid N-oxide / acetonitrile; H2O / 0.33 h
6: 59 percent / 10percent palladium on carbon / benzene / 48 h / Heating
With
Pyridine-2,6-dicarboxylic acid N-oxide; potassium hydroxide; ammonium cerium(IV) nitrate; hydrogen; phenyllithium;
platinum(IV) oxide; palladium on activated charcoal;
In
tetrahydrofuran; methanol; water; acetic acid; acetonitrile; benzene;
DOI:10.1248/cpb.34.4056
