(2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester

Base Information

• Chemical Name: (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester
• CAS No.: 861039-44-3
• Molecular Formula: C₁₈H₂₃BrO₇
• Molecular Weight: 431.28
• Mol file: 861039-44-3.mol

Synonyms:

Chemical Property of (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester

There total 3 articles about (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(3,4-dimethoxyphenyl)butanoic acid (13575-74-1) → (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester (861039-44-3)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; bromine

3: sodium ethylate

With bromine; sodium ethanolate; acetic acid;

DOI:10.1021/ja01277a078

Reference yield:

4-(2-bromo-4,5-dimethoxy-phenyl)-butyric acid (802985-69-9) → (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester (861039-44-3)

Guidance literature:

Multi-step reaction with 2 steps

2: sodium ethylate

With sodium ethanolate;

DOI:10.1021/ja01277a078

Reference yield:

4-(2-bromo-4,5-dimethoxy-phenyl)-butyric acid ethyl ester (500363-75-7) + oxalic acid diethyl ester (95-92-1) → (2-bromo-4,5-dimethoxy-phenethyl)-oxalacetic acid diethyl ester (861039-44-3)

Guidance literature:

With sodium ethanolate;

DOI:10.1021/ja01277a078

upstream raw materials:

4-(2-bromo-4,5-dimethoxy-phenyl)-butyric acid ethyl ester

oxalic acid diethyl ester

4-(3,4-dimethoxyphenyl)butanoic acid

4-(2-bromo-4,5-dimethoxy-phenyl)-butyric acid

Downstream raw materials:

5-(2-bromo-4,5-dimethoxy-phenyl)-2-oxo-valeric acid