Boc-L-trans(βPh)Pro-D-Phe-NHMe

Base Information

• Chemical Name: Boc-L-trans(βPh)Pro-D-Phe-NHMe
• CAS No.: 1353499-18-9
• Molecular Formula: C₂₆H₃₃N₃O₄
• Molecular Weight: 451.566
• Mol file: 1353499-18-9.mol

Synonyms:

Chemical Property of Boc-L-trans(βPh)Pro-D-Phe-NHMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-L-trans(βPh)Pro-D-Phe-NHMe

There total 1 articles about Boc-L-trans(βPh)Pro-D-Phe-NHMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R)-1-(tert-butoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid (123724-21-0,210420-48-7,149252-59-5) + (R)-1-(methylaminocarbonyl)-3-phenylpropanaminium chloride (111321-55-2) → Boc-L-trans(βPh)Pro-D-Phe-NHMe (1353499-18-9)

Guidance literature:

(2S,3R)-1-(tert-butoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid; With (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In acetonitrile; for 0.166667h;

(R)-1-(methylaminocarbonyl)-3-phenylpropanaminium chloride; With N-ethyl-N,N-diisopropylamine; In acetonitrile; for 96h;

DOI:10.1039/c1ob06561k

Reference yield:

Boc-L-trans(βPh)Pro-D-Phe-NHMe (1353499-18-9) → C21H25N3O2

Guidance literature:

With hydrogenchloride; water; In ethyl acetate; at 20 ℃; for 2h;

DOI:10.1039/c1ob06561k

upstream raw materials:

(2S,3R)-1-(tert-butoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid

(R)-1-(methylaminocarbonyl)-3-phenylpropanaminium chloride