C₂₅H₂₀N₄O₃

Base Information

• Chemical Name: C₂₅H₂₀N₄O₃
• CAS No.: 1331784-22-5
• Molecular Formula: C₂₅H₂₀N₄O₃
• Molecular Weight: 424.459
• Mol file: 1331784-22-5.mol

Synonyms:

Chemical Property of C₂₅H₂₀N₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₀N₄O₃

There total 7 articles about C₂₅H₂₀N₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-1,2:5,6-dibenzocycloocta-1,5,7-triene (1144-71-4,77733-42-7) → C25H20N4O3 (1331784-22-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: bromine / chloroform / 0.5 h / Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / Inert atmosphere

2.2: Inert atmosphere

3.1: Dess-Martin periodane / dichloromethane / 0.5 h / Inert atmosphere

4.1: acetic acid / methanol; dichloromethane / 48 h / Inert atmosphere

5.1: methanol / 25 °C / Inert atmosphere

With bromine; Dess-Martin periodane; acetic acid; lithium diisopropyl amide; In tetrahydrofuran; methanol; dichloromethane; chloroform;

DOI:10.1002/cbic.201100117

Reference yield:

4-dibenzocyclooctynol (1027338-06-2) → C25H20N4O3 (1331784-22-5)

Guidance literature:

Multi-step reaction with 3 steps

1: Dess-Martin periodane / dichloromethane / 0.5 h / Inert atmosphere

2: acetic acid / methanol; dichloromethane / 48 h / Inert atmosphere

3: methanol / 25 °C / Inert atmosphere

With Dess-Martin periodane; acetic acid; In methanol; dichloromethane;

DOI:10.1002/cbic.201100117

Reference yield:

11,12-dibromo-5,6,11,12-tetrahydrodibenzo[a,e]cycloocten-5-ol (1027338-08-4) → C25H20N4O3 (1331784-22-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / Inert atmosphere

1.2: Inert atmosphere

2.1: Dess-Martin periodane / dichloromethane / 0.5 h / Inert atmosphere

3.1: acetic acid / methanol; dichloromethane / 48 h / Inert atmosphere

4.1: methanol / 25 °C / Inert atmosphere

With Dess-Martin periodane; acetic acid; lithium diisopropyl amide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/cbic.201100117

upstream raw materials:

11,12-dibromo-5,6,11,12-tetrahydrodibenzo[a,e]cycloocten-5-ol

4-dibenzocyclooctynol

6H-11,12-didehydro-dibenzo[a,e]cyclooctatrien-5-one

(6H-11,1 2-didehydro-dibenzo[a,e]cycloocten-5-ylideneaminooxy)-acetic acid