Technology Process of C17H16FIN4O3
There total 5 articles about C17H16FIN4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-iodo-succinimide; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 12h;
DOI:10.1016/j.bmcl.2014.03.086
- Guidance literature:
-
Multi-step reaction with 5 steps
1: bis-triphenylphosphine-palladium(II) chloride / toluene / 12 h / 100 °C
2: sodium periodate; potassium permanganate / water; 1,4-dioxane / 2 h / 20 °C
3: hydrazine hydrate / methanol / 12 h / 20 °C
4: sodium hydride / N,N-dimethyl-formamide / 0.75 h / 150 °C / Microwave irradiation
5: toluene-4-sulfonic acid; N-iodo-succinimide / methanol; tetrahydrofuran / 12 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; potassium permanganate; sodium periodate; N-iodo-succinimide; hydrazine hydrate; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide; toluene;
1: |Stille Cross Coupling;
DOI:10.1016/j.bmcl.2014.03.086
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium periodate; potassium permanganate / water; 1,4-dioxane / 2 h / 20 °C
2: hydrazine hydrate / methanol / 12 h / 20 °C
3: sodium hydride / N,N-dimethyl-formamide / 0.75 h / 150 °C / Microwave irradiation
4: toluene-4-sulfonic acid; N-iodo-succinimide / methanol; tetrahydrofuran / 12 h / 20 °C
With
potassium permanganate; sodium periodate; N-iodo-succinimide; hydrazine hydrate; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.03.086
