HOC₆H₄CHNC₉OH₄(O)N(C₂H₅)2

Base Information

• Chemical Name: HOC₆H₄CHNC₉OH₄(O)N(C₂H₅)2
• CAS No.: 1257323-67-3
• Molecular Formula: C₂₀H₂₀N₂O₃
• Molecular Weight: 336.39
• Mol file: 1257323-67-3.mol

Synonyms:

Chemical Property of HOC₆H₄CHNC₉OH₄(O)N(C₂H₅)2

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of HOC₆H₄CHNC₉OH₄(O)N(C₂H₅)2

There total 3 articles about HOC₆H₄CHNC₉OH₄(O)N(C₂H₅)2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.8%

salicylaldehyde (90-02-8) + 3-amino-7-(diethylamino)-2H-chromen-2-one (817638-67-8) → HOC6H4CHNC9OH4(O)N(C2H5)2 (1257323-67-3)

Guidance literature:

In ethanol; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.ica.2010.03.058

Reference yield:

4-(Diethylamino)salicylaldehyde (17754-90-4) → HOC6H4CHNC9OH4(O)N(C2H5)2 (1257323-67-3)

Guidance literature:

Multi-step reaction with 3 steps

1: piperidine; acetic acid / butan-1-ol / 12 h / Reflux

2: hydrogenchloride; tin(II) chloride hydrate / water / 20 °C

3: ethanol / 20 °C / Inert atmosphere

With piperidine; hydrogenchloride; tin(II) chloride hydrate; acetic acid; In ethanol; water; butan-1-ol; 3: Schiff base condensation;

DOI:10.1016/j.ica.2010.03.058

Reference yield:

7-(diethylamino)-3-nitronaphthalen-2(1H)-one (118116-71-5) → HOC6H4CHNC9OH4(O)N(C2H5)2 (1257323-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; tin(II) chloride hydrate / water / 20 °C

2: ethanol / 20 °C / Inert atmosphere

With hydrogenchloride; tin(II) chloride hydrate; In ethanol; water; 2: Schiff base condensation;

DOI:10.1016/j.ica.2010.03.058

upstream raw materials:

4-(Diethylamino)salicylaldehyde

salicylaldehyde

3-amino-7-(diethylamino)-2H-chromen-2-one

7-(diethylamino)-3-nitronaphthalen-2(1H)-one