Technology Process of 2-N-ethylamino-1,3-di(4-methylthiophenyl)propane
There total 8 articles about 2-N-ethylamino-1,3-di(4-methylthiophenyl)propane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-N-acetylamino-1,3-di(4-methylthiophenyl)propane;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
Inert atmosphere;
Reflux;
With
sodium hydroxide;
In
tetrahydrofuran; water; isopropyl alcohol;
Cooling with ice;
DOI:10.1016/j.bmc.2010.04.022
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium fluoride; N,N-dimethylammonium chloride / toluene / 24 h / Reflux
2: iron; acetic acid / 2 h / 100 °C
3: 5 h / 190 °C
4: hydrogenchloride; water / methanol / 7 h / Reflux
5: pyridine / 1 h / 20 °C
6: lithium aluminium tetrahydride / tetrahydrofuran; benzene / 3 h / Reflux
With
pyridine; hydrogenchloride; potassium fluoride; lithium aluminium tetrahydride; water; N,N-dimethylammonium chloride; iron; acetic acid;
In
tetrahydrofuran; methanol; toluene; benzene;
1: Henry reaction;
DOI:10.1016/j.bmc.2010.11.054
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium tetrahydroborate; silica gel / dichloromethane; isopropyl alcohol / 0.33 h / 20 °C
2: potassium fluoride; N,N-dimethylammonium chloride / toluene / 24 h / Reflux
3: iron; acetic acid / 2 h / 100 °C
4: 5 h / 190 °C
5: hydrogenchloride; water / methanol / 7 h / Reflux
6: pyridine / 1 h / 20 °C
7: lithium aluminium tetrahydride / tetrahydrofuran; benzene / 3 h / Reflux
With
pyridine; hydrogenchloride; potassium fluoride; sodium tetrahydroborate; lithium aluminium tetrahydride; water; N,N-dimethylammonium chloride; silica gel; iron; acetic acid;
In
tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol; toluene; benzene;
2: Henry reaction;
DOI:10.1016/j.bmc.2010.11.054
