C₂₈H₃₃N₅O₇

Base Information

• Chemical Name: C₂₈H₃₃N₅O₇
• CAS No.: 1376709-47-5
• Molecular Formula: C₂₈H₃₃N₅O₇
• Molecular Weight: 551.599
• Mol file: 1376709-47-5.mol

Synonyms:

Chemical Property of C₂₈H₃₃N₅O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₃N₅O₇

There total 7 articles about C₂₈H₃₃N₅O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C2HF3O2*C15H18N4O4 + N-(Benzyloxycarbonyl)-L-valine 1H-benzotriazol-1-yl ester (126814-51-5) → C28H33N5O7 (1376709-47-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃;

DOI:10.2174/092986612799363172

Reference yield:

BOC-O-benzyl-L-serine (23680-31-1) → C28H33N5O7 (1376709-47-5)

Guidance literature:

Multi-step reaction with 8 steps

1: triethylamine / tetrahydrofuran / 0.25 h / -25 °C

2: tetrahydrofuran; diethyl ether / -15 °C

3: hydrogen bromide / tetrahydrofuran; water / 0.08 h / 20 °C

4: sodium azide / water; dimethyl sulfoxide

5: copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran; water

6: tetrahydrofuran; diethyl ether / 0 °C

7: dichloromethane / 20 °C

8: triethylamine / tetrahydrofuran / 0 °C

With copper(l) iodide; sodium azide; hydrogen bromide; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; dimethyl sulfoxide;

DOI:10.2174/092986612799363172

Reference yield:

tert-butyl N-{(1S)-[(benzyloxy)methyl]-3-diazo-2-oxopropyl}carbamate (193148-60-6) → C28H33N5O7 (1376709-47-5)

Guidance literature:

Multi-step reaction with 6 steps

1: hydrogen bromide / tetrahydrofuran; water / 0.08 h / 20 °C

2: sodium azide / water; dimethyl sulfoxide

3: copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran; water

4: tetrahydrofuran; diethyl ether / 0 °C

5: dichloromethane / 20 °C

6: triethylamine / tetrahydrofuran / 0 °C

With copper(l) iodide; sodium azide; hydrogen bromide; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; dimethyl sulfoxide;

DOI:10.2174/092986612799363172

upstream raw materials:

C₁₉H₂₄N₄O₆

N-(Benzyloxycarbonyl)-L-valine 1H-benzotriazol-1-yl ester

BOC-O-benzyl-L-serine

tert-butyl N-{(1S)-[(benzyloxy)methyl]-3-diazo-2-oxopropyl}carbamate