6-chloro-4-iodopyridine-3-carboxylic acid

Base Information

• Chemical Name: 6-chloro-4-iodopyridine-3-carboxylic acid
• CAS No.: 1211578-80-1
• Molecular Formula: C₆H₃ClINO₂
• Molecular Weight: 283.453
• Mol file: 1211578-80-1.mol

Synonyms:

Chemical Property of 6-chloro-4-iodopyridine-3-carboxylic acid

Chemical Property:

• Boiling Point: 380.7±42.0 °C(Predicted)
• PKA: 1.90±0.10(Predicted)
• Density: 2.193±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

6-Chloro-4-iodonicotinicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-chloro-4-iodopyridine-3-carboxylic acid

There total 1 articles about 6-chloro-4-iodopyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

6-Chloro-3-pyridinecarboxylic acid (5326-23-8) → 6-chloro-4-iodopyridine-3-carboxylic acid (1211578-80-1)

Guidance literature:

6-Chloro-3-pyridinecarboxylic acid; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h;

upstream raw materials:

6-Chloro-3-pyridinecarboxylic acid

Refernces