C₁₄H₁₁NO₅

Base Information

• Chemical Name: C₁₄H₁₁NO₅
• CAS No.: 1019108-70-3
• Molecular Formula: C₁₄H₁₁NO₅
• Molecular Weight: 273.245
• Mol file: 1019108-70-3.mol

Synonyms:

Chemical Property of C₁₄H₁₁NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₁NO₅

There total 1 articles about C₁₄H₁₁NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-cresol (106-44-5) + 5-fluoro-2-nitrobenzoic acid (320-98-9) → C14H11NO5 (1019108-70-3)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃;

DOI:10.1016/j.bmcl.2012.01.014

Reference yield:

C14H11NO5 (1019108-70-3) → C33H38N4O4 (1367362-68-2)

Guidance literature:

Multi-step reaction with 6 steps

1: triethylamine / dichloromethane

2: palladium on activated charcoal; hydrogen / ethanol

3: triethylamine / dichloromethane

4: sodium hydride / N,N-dimethyl-formamide

5: trifluoroacetic acid

6: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane

With palladium on activated charcoal; hydrogen; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.01.014

Reference yield:

C14H11NO5 (1019108-70-3) + D-valine t-butyl ester (2528-15-6,6070-59-3,13211-31-9,21691-52-1) → C23H28N2O6 (1367362-24-0)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1016/j.bmcl.2012.01.014

upstream raw materials:

p-cresol

5-fluoro-2-nitrobenzoic acid

Downstream raw materials:

C₃₃H₃₈N₄O₄

C₂₃H₂₈N₂O₆