3ref,4trans-Diphenyl-cyclopentanol-(1cis)

Base Information

• Chemical Name: 3ref,4trans-Diphenyl-cyclopentanol-(1cis)
• CAS No.: 216484-78-5
• Molecular Formula: C₁₇H₁₈O
• Molecular Weight: 238.329
• Mol file: 216484-78-5.mol

Synonyms:

Chemical Property of 3ref,4trans-Diphenyl-cyclopentanol-(1cis)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3ref,4trans-Diphenyl-cyclopentanol-(1cis)

There total 4 articles about 3ref,4trans-Diphenyl-cyclopentanol-(1cis) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3R,4R)-3,4-diphenylcyclopentanone (216223-19-7) → 3ref,4trans-Diphenyl-cyclopentanol-(1cis) (216484-78-5)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 0.5h; Yield given; Ambient temperature;

DOI:10.1021/jo981231f

Reference yield:

(S)-N-[3-phenyl-2-(E)-propenoyl]-4-isopropyl-1,3-oxazolidine-2-thione (216222-79-6) → 3ref,4trans-Diphenyl-cyclopentanol-(1cis) (216484-78-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₄NOTs / acetonitrile / electroreductive hydrocoupling

2: NaBH₄ / ethanol / 0.5 h / Ambient temperature

With sodium tetrahydroborate; tetraethylammonium tosylate; In ethanol; acetonitrile;

DOI:10.1021/jo981231f

Reference yield:

(E)-1-((S)-4-Isopropyl-2-thioxo-thiazolidin-3-yl)-3-phenyl-propenone → 3ref,4trans-Diphenyl-cyclopentanol-(1cis) (216484-78-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₄NOTs / acetonitrile / electroreductive hydrocoupling

2: NaBH₄ / ethanol / 0.5 h / Ambient temperature

With sodium tetrahydroborate; tetraethylammonium tosylate; In ethanol; acetonitrile;

DOI:10.1021/jo981231f

upstream raw materials:

(3R,4R)-3,4-diphenylcyclopentanone

(S)-N-[3-phenyl-2-(E)-propenoyl]-4-isopropyl-1,3-oxazolidine-2-thione