SJ733

Base Information

Chemical Name:SJ733
CAS No.:1424799-20-1
Molecular Formula:C₂₄H₁₆F₄N₄O₂
Molecular Weight:468.41
Hs Code.:

Synonyms:

Suppliers and Price of SJ733

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
(+)-SJ733 99.45%
100mg
$ 5040.00

ChemScene
(+)-SJ733 99.45%
50mg
$ 3588.00

ChemScene
(+)-SJ733 99.45%
10mg
$ 1188.00

ChemScene
(+)-SJ733 99.45%
5mg
$ 708.00

ChemScene
(+)-SJ733 99.45%
1mg
$ 228.00

Total 4 raw suppliers

Chemical Property of SJ733

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(+)-SJ733 99.45% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of SJ733

There total 15 articles about SJ733 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid

: 53312-81-5
3-cyano-4-fluoroaniline

: 1424799-20-1
rac-(3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide

Guidance literature:: With pyridine; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; at 0 - 20 ℃; for 16h; Reagent/catalyst; Solvent; Temperature;
DOI:10.1021/acs.oprd.7b00046

Reference yield:

: 1424799-68-7
(pyridine-3-ylmethylene)(2,2,2-trifluoroethyl)amine

: 1424799-20-1
rac-(3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 16 h / -20 - 83 °C / Reflux

2: trichlorophosphate / acetonitrile / 3 h / Reflux

With trichlorophosphate; In acetonitrile;

Reference yield:

: 500-22-1
3-pyridinecarboxaldehyde

: 1424799-20-1
rac-(3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / toluene; water / 20 °C / Cooling with ice

2: acetic acid / 16 h / Reflux

3: trichlorophosphate / acetonitrile / 3 h / Reflux

With acetic acid; sodium hydroxide; trichlorophosphate; In water; toluene; acetonitrile;
DOI:10.1021/acs.jmedchem.6b00752