Technology Process of GA9
There total 6 articles about GA9 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.) hydrogen sulphide / 1.) THF, CH2Cl2, room temperature, 40 h, 2.) pyridine, 5 min
2: 35 mg / tri-n-butylstannane, 2,2'-azobis(2-methylpropionitrile) / toluene / 1 h / Heating
3: 61 mg / 2M NaOH / dioxane; H2O / 1.) reflux, 15 h, 2.) stream-bath, 0.5 h
With
sodium hydroxide; 2,2'-azobis(isobutyronitrile); hydrogen sulfide; tri-n-butyl-tin hydride;
In
1,4-dioxane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 35 mg / tri-n-butylstannane, 2,2'-azobis(2-methylpropionitrile) / toluene / 1 h / Heating
2: 61 mg / 2M NaOH / dioxane; H2O / 1.) reflux, 15 h, 2.) stream-bath, 0.5 h
With
sodium hydroxide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride;
In
1,4-dioxane; water; toluene;
- Guidance literature:
-
With
sodium hydroxide;
In
1,4-dioxane; water;
1.) reflux, 15 h, 2.) stream-bath, 0.5 h;