N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid

Base Information

• Chemical Name: N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid
• CAS No.: 67451-37-0
• Molecular Formula: C₁₁H₉ClN₂O₈S
• Molecular Weight: 364.72
• Mol file: 67451-37-0.mol

Synonyms:

Chemical Property of N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid

There total 4 articles about N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-Dinitro-4-(methyl-sulfonyl)-chlorbenzol (4726-15-2) → N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid (67451-37-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Fe, aq. HCl / ethanol / Heating

2: Et₃N / dimethylformamide

3: aq. NaOH

With hydrogenchloride; sodium hydroxide; iron; triethylamine; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00207a016

Reference yield:

2,6-Dinitro-4-(methyl-sulfonyl)-phenol (53559-50-5) → N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid (67451-37-0)

Guidance literature:

Multi-step reaction with 4 steps

1: POCl₃ / dimethylformamide

2: Fe, aq. HCl / ethanol / Heating

3: Et₃N / dimethylformamide

4: aq. NaOH

With hydrogenchloride; sodium hydroxide; iron; triethylamine; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00207a016

Reference yield:

2-Chloro-5-methanesulfonyl-benzene-1,3-diamine (67451-17-6) → N-[2-Chloro-5-methanesulfonyl-3-(oxalyl-amino)-phenyl]-oxalamic acid (67451-37-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / dimethylformamide

2: aq. NaOH

With sodium hydroxide; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1021/jm00207a016

upstream raw materials:

N-[2-Chloro-3-(ethoxyoxalyl-amino)-5-methanesulfonyl-phenyl]-oxalamic acid ethyl ester

2,6-Dinitro-4-(methyl-sulfonyl)-chlorbenzol

2,6-Dinitro-4-(methyl-sulfonyl)-phenol

2-Chloro-5-methanesulfonyl-benzene-1,3-diamine