hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid

Base Information

• Chemical Name: hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid
• CAS No.: 97868-87-6
• Molecular Formula: C₂₂H₂₇N₃O₆*ClH
• Molecular Weight: 465.934
• Mol file: 97868-87-6.mol

Synonyms:

Chemical Property of hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid

There total 3 articles about hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

N-benzyloxycarbonyl-2-aminoethyl ester of Nα-tert-butyloxycarbonyl-Nγ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid (97868-85-4) → hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of Nγ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid (97868-87-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

Reference yield:

benzyl 2-hydroxyethylcarbamate (77987-49-6) → hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of Nγ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid (97868-87-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / dicyclohexylcarbodiimide / ethyl acetate / 24 h / Ambient temperature

2: 68 percent / HCl / dioxane / 1 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; In 1,4-dioxane; ethyl acetate;

Reference yield:

(2S)-4-(benzyloxycarbonyl)amino-2-(tert-butoxycarbonyl)aminobutyric acid (3350-20-7,47461-65-4,70882-68-7) → hydrochloride of N-benzyloxycarbonyl-2-aminoethyl ester of Nγ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid (97868-87-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / dicyclohexylcarbodiimide / ethyl acetate / 24 h / Ambient temperature

2: 68 percent / HCl / dioxane / 1 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; In 1,4-dioxane; ethyl acetate;

upstream raw materials:

N-benzyloxycarbonyl-2-aminoethyl ester of N^α-tert-butyloxycarbonyl-N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid

benzyl 2-hydroxyethylcarbamate

(2S)-4-(benzyloxycarbonyl)amino-2-(tert-butoxycarbonyl)aminobutyric acid

Downstream raw materials:

N-benzyloxycarbonyl-2-aminoethyl ester of N^α-palmitoyl-N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid

N-benzyloxycarbonyl-2-aminoethyl ester of N^α-palmitoyl-N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyryl-N^γ-benzyloxycarbonyl-L-α,γ-diaminobutyric acid