t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Base Information

Chemical Name:t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate
CAS No.:163402-67-3
Molecular Formula:C₃₂H₃₃N₅O₄P₂
Molecular Weight:613.593
Hs Code.:

Synonyms:

Suppliers and Price of t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

There total 8 articles about t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₂H₃₃N₅O₃P₂

: 163402-67-3
t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Guidance literature:: With tert.-butylhydroperoxide; Yield given;
DOI:10.1016/0040-4039(95)00326-8

Reference yield:

: 4412-91-3
furan-3-methanol

: 163402-67-3
t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Guidance literature:: Multi-step reaction with 7 steps

1.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / -10 °C

2.1: sodium hydride / dimethylformamide

2.2: 51 percent / dimethylformamide / 2.5 h

3.1: 81 percent / sodium azide / dimethylformamide / 72 h / 20 °C

4.1: 80 percent / tetrahydrofuran / 5 h / 60 °C

5.1: Rose Bengal; oxygen / ethanol; methanol; CH₂Cl₂ / 3 h / -78 °C / Irradiation

5.2: 87 percent / sodium borohydride / ethanol; methanol; CH₂Cl₂ / 3 h / -78 °C

6.1: 1H-tetrazole / acetonitrile; CH₂Cl₂ / 2 h

7.1: 0.33 g / t-butyl hydroperoxide / acetonitrile; CH₂Cl₂; H₂O / 2 h

With pyridine; 1H-tetrazole; tert.-butylhydroperoxide; sodium azide; oxygen; phosphorus tribromide; rose bengal; sodium hydride; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; 1.1: Bromination / 2.1: Metallation / 2.2: Substitution / 3.1: Substitution / 4.1: Staudinger reduction / 5.1: Oxidation / 5.2: Reduction / 6.1: phosphitylation / 7.1: Oxidation;
DOI:10.1016/S0040-4020(97)00466-3

Reference yield:

: 63184-61-2
3-(bromomethyl)furan

: 163402-67-3
t-butyl-2-(6-triphenyliminophosphoranopurin-9-ylmethyl)-Z-but-2-ene-1,4-diyl cyclophosphate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / dimethylformamide

1.2: 51 percent / dimethylformamide / 2.5 h

2.1: 81 percent / sodium azide / dimethylformamide / 72 h / 20 °C

3.1: 80 percent / tetrahydrofuran / 5 h / 60 °C

4.1: Rose Bengal; oxygen / ethanol; methanol; CH₂Cl₂ / 3 h / -78 °C / Irradiation

4.2: 87 percent / sodium borohydride / ethanol; methanol; CH₂Cl₂ / 3 h / -78 °C

5.1: 1H-tetrazole / acetonitrile; CH₂Cl₂ / 2 h

6.1: 0.33 g / t-butyl hydroperoxide / acetonitrile; CH₂Cl₂; H₂O / 2 h

With 1H-tetrazole; tert.-butylhydroperoxide; sodium azide; oxygen; rose bengal; sodium hydride; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; 1.1: Metallation / 1.2: Substitution / 2.1: Substitution / 3.1: Staudinger reduction / 4.1: Oxidation / 4.2: Reduction / 5.1: phosphitylation / 6.1: Oxidation;
DOI:10.1016/S0040-4020(97)00466-3