N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Base Information

Chemical Name:N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
CAS No.:210302-17-3
Molecular Formula:C₁₆H₁₀F₂N₆O
Molecular Weight:340.292
Hs Code.:

N<sup>5</sup>,N<sup>6</sup>-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Synonyms:

Suppliers and Price of N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BAM15
100mg
$ 95.00

TRC
BAM15
500mg
$ 375.00

Tocris
BAM15 ≥98%(HPLC)
10
$ 174.00

Tocris
BAM15 ≥98%(HPLC)
50
$ 716.00

DC Chemicals
BAM15
1g
$ 1500.00

DC Chemicals
BAM15
250 mg
$ 750.00

DC Chemicals
BAM15
100 mg
$ 450.00

Crysdot
BAM15 98%
25mg
$ 306.00

ChemScene
BAM15 99.26%
50mg
$ 400.00

ChemScene
BAM15 99.26%
100mg
$ 600.00

Total 47 raw suppliers

Chemical Property of N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Chemical Property:

Boiling Point:421.7±55.0 °C(Predicted)
Density:1.548±0.06 g/cm3(Predicted)

Purity/Quality:

≥98% ^*data from raw suppliers

BAM15 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description BAM15 (210302-17-3) is a mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria.)1,2 Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane.2 Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models.3 Reverses diet-induced obesity and insulin resistance in mice.4 Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.5
Uses BAM 15, is a mitochondrial protonophore uncoupler that does not depolarize the plasma membrane and protects mice from acute renal ischemic-reperfusion injury.

Technology Process of N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

There total 1 articles about N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%