(±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid

Base Information

• Chemical Name: (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid
• CAS No.: 895127-63-6
• Molecular Formula: C₂₂H₃₂O₃
• Molecular Weight: 344.494

Synonyms:

Chemical Property of (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid

Chemical Property:

Purity/Quality:

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Technology Process of (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid

There total 4 articles about (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

docosahexaenoic acid (6217-54-5) → (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid (895127-63-6) + cis-14,15-epoxyeicosatrienoic acid (197508-62-6,81276-03-1)

Guidance literature:

With human recombinant cytochrome P₄₅₀ 2E₁; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

Reference yield: 54.0%

docosahexaenoic acid (6217-54-5) → (±)-10,11-epoxy-4Z,7Z,13Z,16Z,19Z-docosapentaenoic acid (895127-65-8) + 7,8-epoxydocosapentaenoic acid (895127-66-9) + 13,14-epoxydocosapentaenoic acid (895127-64-7) + (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid (895127-63-6) + all-cis 19R,20S-epoxydocosapentaenoic acid

Guidance literature:

With human recombinant cytochrome P₄₅₀ 1A₂; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

Reference yield: 47.0%

docosahexaenoic acid (6217-54-5) → (±)-10,11-epoxy-4Z,7Z,13Z,16Z,19Z-docosapentaenoic acid (895127-65-8) + 13,14-epoxydocosapentaenoic acid (895127-64-7) + (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid (895127-62-5) + (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid (895127-63-6)

Guidance literature:

With human recombinant cytochrome P₄₅₀ 2C₈; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

upstream raw materials:

docosahexaenoic acid

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