2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride

Base Information

• Chemical Name: 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride
• CAS No.: 108895-73-4
• Molecular Formula: C₃₆H₃₉O₉P
• Molecular Weight: 646.674
• Mol file: 108895-73-4.mol

Synonyms:

Chemical Property of 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride

There total 6 articles about 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-methoxytetrahydro-2H-pyran (3879-79-6,17791-37-6,19488-61-0,53008-63-2,69237-94-1,69237-95-2,71526-33-5,83462-67-3,84799-77-9,103421-29-0,103421-30-3,139241-42-2,61330-62-9) → 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-mannopyranosylphosphonic acetic anhydride (108895-73-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent / conc. H₂SO₄ / acetic acid / 2 h / Ambient temperature

2: CF₃SO₂OSiMe₃ / 0.5 h / 80 °C

3: H₂O

With trimethylsilyl trifluoromethanesulfonate; sulfuric acid; water; In acetic acid;

DOI:10.1021/jm00391a020

Reference yield:

trimethylsilyl<2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-glucopyranosyl>phosphonic acetic anhydride → 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-glucopyranosylphosphonic acetic anhydride (108895-73-4)

Guidance literature:

With water;

DOI:10.1021/jm00391a020

Reference yield:

C39H47O9PSi → 2,3,4,6-tetrakis-O-(phenylmethyl)-α-D-galactopyranosylphosphonic acetic anhydride (108895-73-4)

Guidance literature:

With water;

DOI:10.1021/jm00391a020

upstream raw materials:

2,3,4,6-tetrakis-O-(phenylmethyl)-1-O-acetyl-α-D-galactopyranose

(2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-methoxytetrahydro-2H-pyran

2,3,4,6-tetra-O-benzyl-1-O-acetyl-α-D-mannopyranose