Technology Process of 5-(2-methoxyphenyl)-3,3-dimethyldihydrofuran-2(3H)-one
There total 3 articles about 5-(2-methoxyphenyl)-3,3-dimethyldihydrofuran-2(3H)-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
aluminum oxide; sodium hypochlorite; sodium acetate; pyridinium chlorochromate;
In
dichloromethane;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/chem.201101186
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diphenylphosphinous acid methyl ester; hydrogen; rhodium(I) dicarbonyl acetylacetonate / tetrahydrofuran / 16 h / 60 °C / 30003 Torr / Inert atmosphere; Autoclave; Molecular sieve
2: aluminum oxide; sodium hypochlorite; sodium acetate; pyridinium chlorochromate / dichloromethane / 12 h / 20 °C / Inert atmosphere
With
aluminum oxide; sodium hypochlorite; diphenylphosphinous acid methyl ester; hydrogen; sodium acetate; pyridinium chlorochromate; rhodium(I) dicarbonyl acetylacetonate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/chem.201101186
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tin(II) chloride dihdyrate; sodium iodide / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere
2: diphenylphosphinous acid methyl ester; hydrogen; rhodium(I) dicarbonyl acetylacetonate / tetrahydrofuran / 16 h / 60 °C / 30003 Torr / Inert atmosphere; Autoclave; Molecular sieve
3: aluminum oxide; sodium hypochlorite; sodium acetate; pyridinium chlorochromate / dichloromethane / 12 h / 20 °C / Inert atmosphere
With
aluminum oxide; sodium hypochlorite; diphenylphosphinous acid methyl ester; tin(II) chloride dihdyrate; hydrogen; sodium acetate; pyridinium chlorochromate; sodium iodide; rhodium(I) dicarbonyl acetylacetonate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/chem.201101186
