N-butyl-2-bromo-4-methylaniline

Base Information

• Chemical Name: N-butyl-2-bromo-4-methylaniline
• CAS No.: 1019542-99-4
• Molecular Formula: C₁₁H₁₆BrN
• Molecular Weight: 242.159
• Mol file: 1019542-99-4.mol

Synonyms:

Chemical Property of N-butyl-2-bromo-4-methylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-butyl-2-bromo-4-methylaniline

There total 7 articles about N-butyl-2-bromo-4-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-butyl-N-(2-bromo-4-methylphenyl)hydrazine (1338369-83-7) → N-butyl-2-bromo-4-methylaniline (1019542-99-4)

Guidance literature:

With [Ru(bpyrz)3](PF₆)2*2H₂O; In methanol; acetonitrile; at 20 ℃; for 15h; Air; Visible light; Irradiation;

DOI:10.1055/s-0030-1260082

Reference yield:

N-tert-butoxycarbonyl-N'-(2-bromo-4-methylphenyl)hydrazine (1338369-90-6) → N-butyl-2-bromo-4-methylaniline (1019542-99-4)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine; N-Bromosuccinimide / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2: tetrahydrofuran / 0.25 h / -100 °C / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / 0 °C / Inert atmosphere

4: [Ru(bpyrz)3](PF₆)2*2H₂O / methanol; acetonitrile / 15 h / 20 °C / Air; Visible light; Irradiation

With pyridine; N-Bromosuccinimide; [Ru(bpyrz)3](PF₆)2*2H₂O; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;

DOI:10.1055/s-0030-1260082

Reference yield:

N-tert-butoxycarbonyl-N'-(2-bromo-4-methylphenyl)diazene (1338369-61-1) → N-butyl-2-bromo-4-methylaniline (1019542-99-4)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / 0.25 h / -100 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 0 °C / Inert atmosphere

3: [Ru(bpyrz)3](PF₆)2*2H₂O / methanol; acetonitrile / 15 h / 20 °C / Air; Visible light; Irradiation

With [Ru(bpyrz)3](PF₆)2*2H₂O; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;

DOI:10.1055/s-0030-1260082

upstream raw materials:

N-tert-butoxycarbonyl-N'-(2-bromo-4-methylphenyl)hydrazine

N-tert-butoxycarbonyl-N'-(2-bromo-4-methylphenyl)diazene

N-tert-butoxycarbonyl-N'-(2-bromo-4-methylphenyl)-N'-butylhydrazine

N-butyl-N-(2-bromo-4-methylphenyl)hydrazine