17-epi-Testosterone-d3

Base Information

• Chemical Name: 17-epi-Testosterone-d3
• CAS No.: 171199-96-5
• Molecular Formula: C₁₉H₂₈O₂
• Molecular Weight: 297.359
• Mol file: 171199-96-5.mol

Synonyms:

Chemical Property of 17-epi-Testosterone-d3

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

17-epi-Testosterone-d3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 17-epi-Testosterone-d3 is the labelled analog of 17-epi-Testosterone.Testosterone (T155000) and epitestosterone (T155005) are endogenous steroids that differ in the configuration of the hydroxyl-beari ng carbon at C-17.

Technology Process of 17-epi-Testosterone-d3

There total 21 articles about 17-epi-Testosterone-d3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

[1α,2,2,4,6,6,16,16-2H8]androst-4-ene-3,17-dione (4273-45-4) → [1α,2,2,4,6,6,16,16,17α-2H9]androst-4-en-17β-ol-3-one (638163-35-6,165195-35-7,171199-96-5,204244-83-7)

Guidance literature:

With sodium borodeuteride; In water-d2; at 0 ℃; for 2h;

DOI:10.1016/S0039-128X(03)00102-8

Reference yield: 93.0%

3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy><16,16,17α-(2)H3>androsta-3,4-diene-17β-ol (103708-02-7) → <16,16,17α-(2)H3> testosterone (77546-39-5,171199-96-5)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; for 6.5h; Heating;

Reference yield: 58.5%

[1α,2,2,4,6,6,16,16,17α-2H9]androst-4-en-17β-ol-3-one (638163-35-6,165195-35-7,171199-96-5,204244-83-7) → [1α,16,16,17α-2H4]androst-4-en-17β-ol-3-one (638163-36-7,171199-96-5)

Guidance literature:

In methanol; sulfuric acid; at 55 ℃; for 48h;

DOI:10.1016/S0039-128X(03)00102-8

upstream raw materials:

3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy><16,16,17α-(2)H3>androsta-3,4-diene-17β-ol

Androstenedione

3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>androsta-3,4-diene-17-one

[16,16,17-2H3]-17α-benzoyloxyandrost-4-en-3-one

Downstream raw materials:

[1α,16,16,17α-2H4]androst-4-en-17β-ol-3-one

[1α,16,16,17α-2H4]androst-4-en-6β,17β-diol-3-one

Refernces

• 1、 Furuta, Takashi,Suzuki, Atsushi,Matsuzawa, Mitsuhiro,Shibasaki, Hiromi,Kasuya, Yasuji. "Syntheses of stable isotope-labeled 6β-hydroxycortisol, 6β-hydroxycortisone, and 6β-hydroxytestosterone". . p. 693 - 703. Retrieved 2007/10/03.
• 2、 Jarman, Michael,McCague, Raymond. "The Selective Protection of the 3-Ketone Functions of Steroids as Heptafluoro-p-tolyl Enol Ethers". . p. 1129 - 1134. Retrieved 2007/10/02.