2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester

Base Information

Chemical Name:2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester
CAS No.:1353971-44-4
Molecular Formula:C₁₅H₂₂N₂O₂
Molecular Weight:262.352
Hs Code.:
DSSTox Substance ID:DTXSID601146756
Mol file:1353971-44-4.mol

Synonyms:1353971-44-4;2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester;Benzyl 2-((methylamino)methyl)piperidine-1-carboxylate;benzyl 2-(methylaminomethyl)piperidine-1-carboxylate;SCHEMBL10154291;DTXSID601146756;AM93712;Benzyl2-((methylamino)methyl)piperidine-1-carboxylate;2-methylaminomethylpiperidine-1-carboxylic acid benzyl ester;1-Piperidinecarboxylic acid, 2-[(methylamino)methyl]-, phenylmethyl ester

Suppliers and Price of 2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl2-((methylamino)methyl)piperidine-1-carboxylate 97%
1g
$ 809.00

Total 1 raw suppliers

Chemical Property of 2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:262.168127949
Heavy Atom Count:19
Complexity:277

Purity/Quality:: Benzyl2-((methylamino)methyl)piperidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CNCC1CCCCN1C(=O)OCC2=CC=CC=C2

Technology Process of 2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester

There total 5 articles about 2-Methylaminomethyl-piperidine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₂₆N₂O₂

: 1353971-44-4
C₁₅H₂₂N₂O₂

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾; Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmcl.2020.127496

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 1353971-44-4
C₁₅H₂₂N₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: dichloromethane / 2 h / 20 °C

2.1: Dess-Martin periodane / dichloromethane / 1.17 h

2.2: 1 h / 20 °C

3.1: Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ / tetrahydrofuran / 0.5 h / 20 °C

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾; Dess-Martin periodane; Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2020.127496

Reference yield:

: 105706-75-0
1-benzyloxycarbonyl-2-hydroxymethylpiperidine

: 1353971-44-4
C₁₅H₂₂N₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: Dess-Martin periodane / dichloromethane / 1.17 h

1.2: 1 h / 20 °C

2.1: Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ / tetrahydrofuran / 0.5 h / 20 °C

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾; Dess-Martin periodane; Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2020.127496