methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate

Base Information

• Chemical Name: methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate
• CAS No.: 1202901-91-4
• Molecular Formula: C₃₄H₄₀BrN₃O₆
• Molecular Weight: 666.612
• Mol file: 1202901-91-4.mol

Synonyms:

Chemical Property of methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate

There total 1 articles about methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

(S)-2-benzyl-3-(4-bromobenzylamino)-2-hydroxy-N-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)propanamide (1202901-89-0) + (S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid (162537-11-3) → methyl (S)-1-(((S)-2-benzyl-2-hydroxy-3-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-ylamino)-3-oxopropyl)(4-bromobenzyl)amino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate (1202901-91-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 60 ℃; optical yield given as %de;

DOI:10.1021/jm901165g

upstream raw materials:

(S)-2-benzyl-3-(4-bromobenzylamino)-2-hydroxy-N-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)propanamide

(S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid