3-(2,3-dihydroxypropoxy)karanjonol

Base Information

• Chemical Name: 3-(2,3-dihydroxypropoxy)karanjonol
• CAS No.: 1244042-49-6
• Molecular Formula: C₂₀H₁₆O₆
• Molecular Weight: 352.343
• Mol file: 1244042-49-6.mol

Synonyms:

Chemical Property of 3-(2,3-dihydroxypropoxy)karanjonol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2,3-dihydroxypropoxy)karanjonol

There total 2 articles about 3-(2,3-dihydroxypropoxy)karanjonol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

7-hydroxy-8-phenylfuro[2,3-h]benzopyran-6-one (4439-65-0) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 3-(2,3-dihydroxypropoxy)karanjonol (1244042-49-6)

Guidance literature:

7-hydroxy-8-phenylfuro[2,3-h]benzopyran-6-one; With potassium carbonate; In acetone; for 0.5h; Inert atmosphere;

epichlorohydrin; In acetone; for 8h; Inert atmosphere; Reflux;

With silica gel; In hexane; ethyl acetate;

DOI:10.1007/s00044-010-9387-1

Reference yield:

karanjin (521-88-0) → 3-(2,3-dihydroxypropoxy)karanjonol (1244042-49-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: boron tribromide / dichloromethane / 4 h / -78 - 20 °C / Inert atmosphere

2.1: potassium carbonate / acetone / 0.5 h / Inert atmosphere

2.2: 8 h / Inert atmosphere; Reflux

With boron tribromide; potassium carbonate; In dichloromethane; acetone;

DOI:10.1007/s00044-010-9387-1

upstream raw materials:

karanjin

7-hydroxy-8-phenylfuro[2,3-h]benzopyran-6-one

epichlorohydrin

Refernces